COOMBS, DIRECT 0000361

The Direct Coomb’s Test (DAT or Direct Antiglobulin Test) helps to identfy the cause of hemolytic anemia as caused by an autoimmune disease such as immunoglobulin, complement, or both coating the red blood cell and mediating cellular destruction. This test is also positive in the setting of transfusion reactions and ingestion of certain drugs. When a newborn shows signs of hemolytic disease.